Largest Manufacturers
York County's rich manufacturing history continues today. Companies large and small are thriving here thanks to a dedicated workforce and access to new technologies.
| Company | Employees | City | NAICS Code (2012) | Primary Product or Service |
| Schaeffler Group USA, Inc | 946 | Fort Mill | 332991 | Manufacturer of Automotive Engine Components |
| Shutterfly, Inc. | 500 | Fort Mill | 323111 | Internet Based Image Publishing Service |
| Cummins-Meritor | 500 | York | 336390 | Manufacturer of Brakes and Axles for Light and Commercial Vehicles |
| New-Indy Containerboard LLC | 425 | Catawba | 322219 | Manufacturer of Recycled Containerboard for Corrugated Boxes |
| Atlas Copco USA - Power Technique | 400 | Rock Hill | 333912 | Manufacturer of Industrial Air and Gas Compressors |
| Maclean Power Systems - York | 375 | York | 334419 | High Voltage Insulators and Protection Products |
| Stanley Black & Decker - Manufacturing | 306 | Fort Mill | 332510 | Manufacturer of Power Tools |
| Transaxle Manufacturing of America | 250 | Rock Hill | 336390 | Manufacturer of Transaxles for Small Tractors and Utility Vehicles |
| Cirtec Medical | 250 | Rock Hill | 326299 | Manufacturer of Rubber and Silicone Products for Medical Industry |
| C-A-T Resources, LLC | 230 | Rock Hill | 314999 | Manufacturer of Tourniquets for Military and First Responders |
| Britax Child Safety | 210 | Fort Mill | 339999 | Stroller and Child Safety Equipment Distribution |
| Performance Friction Corporation | 200 | Clover | 336310 | Manufacturer of Carbon Metallic Disc Brake Pads and Rotors |
| Coroplast | 199 | Rock Hill | 322220 | Adhesive Tape for Automotive Industry |
| 3D Systems - Headquarters | 199 | Rock Hill | 333316 | Corporate Headquarters and Manufacturer - 3D Printers and Software |
| Elkem Silicones USA | 198 | York | 325110 | Silicone Manufacturing |
| Filtration Group LLC | 170 | York | 333413 | Manufacturer of Air Filters for HVAC |
| Honeywell Safety Products USA, Inc. | 153 | Clover | 339113 | Manufacturer of Rubber Gloves |
| C.M. Steel, Inc. | 150 | York | 332312 | Structural & Miscellaneous Fabricator |
| Alliance Plastics, LLC | 150 | Rock Hill | 326112 | Stretch Film Products |
| Sherer Dental Laboratory Inc | 120 | Rock Hill | 339116 | Fabricate Dental Prosthetics |
| Oldcastle Building Envelope | 115 | Rock Hill | 327320 | Manufacturer of Custom Engineered Windows, Walls |
| Fomas USA, Inc. | 109 | York | 331110 | Manufacturer of Rolled Seamless Steel Rings |
| Samuel Packaging Systems | 104 | Fort Mill | 332999 | Manufacturer of Plastic Strapping |
| SEM Products | 100 | Rock Hill | 325510 | Paint, Coatings and Adhesives |
| Bedgear, LLC | 100 | Rock Hill | 337910 | Performance Bedding Essentials |